Table 2

Differential diagnosis of the acquired sensory neuronopathies

OnsetDisease association
ParaneoplasticSubacute–chronicSmall cell lung cancer, bronchial carcinoma, breast cancer, ovarian cancer, lymphoma, neuroendocrine tumours, sarcoma
InflammatorySubacute–chronicSjögren's syndrome, rheumatoid arthritis, systemic lupus erythematosus, autoimmune hepatitis
Infection relatedSubacuteHIV (also EBV, VZV, measles, HTLV-1)
MedicationSubacute–chronicPlatinum based chemotherapy (cisplatin, oxaliplatin, carboplatin), antibiotic toxicity has been suggested
Vitamin associatedSubacute–chronicVitamin B6 (pyridoxine) toxicity
IdiopathicChronicNot known
  • EBV, Epstein-Barr virus; HTLV-1, human T cell lymphotropic virus type 1; VZV, varicella zoster virus.