TableĀ 2

Drugs to avoid in patients with Parkinson's disease

AvoidConsider instead
Antiemetics
Prochlorperazine
Chlorpromazine
Metoclopramide
Cinnarizine
Nabilone
Hyoscine hydrobromide
Domperidone (please note MHRA advice)
Ondansetron (not to be used with apomorphine)
Cyclizine
Antipsychotics
Amisulpride
Chlorpromazine
Fluphenazine
Haloperidol
Lorazepam and diazepam
Sertraline
Quetiapine
Mirtazapine
  • The drugs in the left hand column may worsen the symptoms of Parkinson's disease and increase the risk of neuroleptic malignant-like syndrome because they block dopamine receptors. The drugs in the right hand column are safer alternatives. This is not an exhaustive list and readers should refer to the British National Formulary or a pharmacist. MHRA, Medical and Healthcare products Regulatory Agency