Causes of tumefactive demyelination1 3 6
| Cause | Diagnosis |
|---|---|
| Inflammatory | Multiple sclerosis, systemic lupus erythematosus, sarcoidosis, Sjögren's syndrome, Behçet's disease, neuromyelitis optica |
| Infection | HIV, syphilis |
| Drugs | Tacrolimus |
| Paraneoplastic | Germ cell cancer, lymphoma, renal cell carcinoma |
| Primary demyelinating disease | Acute disseminated encephalomyelitis, myelinoclastic diffuse sclerosis (Schilder's disease) |