Table 1

How to interpret syphilis serology

ELISA IgG/IgMTPPA or TPHAVDRL or RPR
Never
Early + +
Secondary + + +
Late + +
Treated + +
Reinfected + + +
False-positive ELISA +
False-positive TPPA/TPHA +
False-positive RPR +
  • RPR, rapid-plasma reagin; TPHA, Treponema pallidum haemagglutination; TPPA, Treponema pallidum particle agglutination; VDRL, venereal disease research laboratory.