High-risk PFO | PFO with atrial septal aneurysm or PFO without atrial septal aneurysm but with spontaneous right-to-left shunt or PFO without atrial septal aneurysm but with large shunt during Valsalva manoeuvre |
Low-risk PFO | PFO without atrial septal aneurysm with small or moderate shunt size during Valsalva manoeuvre |
Based on Carroll et al.23
PFO, patent foramen ovale.