Neuropathy | Chronicity | Main features | Antibodies | Immunoglobulin class |
AMAN | Acute | Pure motor | GM1, GD1a | IgG |
Miller Fisher syndrome | Acute | Ataxia, ophthalmoplegia | GQ1b, GT1a | IgG |
Acute sensory ataxic neuropathy | Acute | Sensory, ataxia | GD1b or GQ1b | IgG |
Pharyngeal–cervical–brachial weakness | Acute | Oropharyngeal, neck and shoulder weakness | GT1a>GQ1b | IgG |
MMNCB | Chronic | Motor, asymmetrical upper limb predominant | GM1, complex GM1:GalC | IgM |
CANOMAD, CANDA | Chronic | Sensory ataxic | GD3, GD1B, GT1b, GQ1b (disialosyl antibodies) | IgM |
Adapted from Delmont et al.19
AMAN, acute motor axonal neuropathy; CANDA, chronic ataxic neuropathy with disialosyl antibodies; CANOMAD, chronic ataxic neuropathy with ophthalmoplegia, IgM paraprotein and anti-disialosyl antibodies; GM:GalC, complex of GM1 and galactocerebroside; MMNCB, multifocal motor neuropathy with conduction block.