Actionable events in all steroid-sparing agents
| Event | Action |
| White blood cell count<3.5×109/L | Withhold until discussion with lead clinician |
| Neutrophils<1.6×109/L | |
| Unexplained eosinophilia>0.5×109/L | |
| Platelets<140×109/L | |
| Creatinine>30% above baseline or eGFR <60 mL/min/1.73 m2 | |
| ALT, AST>100 IU/L | |
| Unexplained fall in serum albumin | |
| Rash or oral ulceration | |
| MCV>105 fL | Check and treat B12, folate, thyroid function. If normal, withhold until discussion with lead clinician |
| Abnormal bruising or severe sore throat | Withhold until FBC available and discuss with lead clinician |
ALT, alanine transaminase; AST, aspartate aminotransferase; eGFR, estimated glomerular filtration rate; FBC, full blood count; MCV, mean cell volume; WBC, white blood cell.