[Recurrent ischemic strokes revealing Lyme meningovascularitis]

Rev Neurol (Paris). 2009 Mar;165(3):273-7. doi: 10.1016/j.neurol.2008.06.010. Epub 2008 Aug 28.
[Article in French]

Abstract

Introduction: Infectious vascularitis is an unusual cause of ischemic stroke (IS). We report a case of Lyme meningovascularitis complicated with multiple IS.

Case report: A 64-year-old man, without any cardiovascular risk factor, was admitted for a right hemiparesia with a left thalamic hypodensity on the initial cerebral CT scan. No cause for this presumed IS could be identified. Later, the patient developed cognitive impairment and a bilateral cerebellar syndrome. Multiple infarcts and multiple intracranial stenosis were seen on cerebral MRI with magnetic resonance angiography (MRA). Cerebrospinal fluid tests showed meningitis and positive Lyme serology with an intrathecal specific anti-Borrelia antibody index. Antibiotic treatment was followed by good biological and partial clinicoradiological outcome.

Conclusion: The diagnosis of Lyme neuroborreliosis should be entertained as a possible cause of IS in highly endemic zones.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Bacterial / analysis
  • Borrelia / immunology
  • Brain Ischemia / complications*
  • Brain Ischemia / diagnosis
  • Brain Ischemia / etiology*
  • Cerebellar Diseases / diagnostic imaging
  • Cerebellar Diseases / etiology
  • Cerebral Infarction / diagnostic imaging
  • Cerebral Infarction / etiology
  • Cognition Disorders / etiology
  • Constriction, Pathologic / diagnostic imaging
  • Constriction, Pathologic / etiology
  • Humans
  • Lyme Neuroborreliosis / complications*
  • Lyme Neuroborreliosis / diagnosis
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Paresis
  • Recurrence
  • Stroke / diagnosis
  • Stroke / etiology*
  • Thalamus / diagnostic imaging
  • Tomography, X-Ray Computed

Substances

  • Antibodies, Bacterial