Abstract
Fifteen cases of acute ciguatera poisoning were subjected to electrical studies on the sural and common peroneal nerves. Significant slowing of sensory conduction velocity and prolongation of the absolute refractory, relative refractory and supernormal periods were recorded. These findings indirectly suggest that ciguatoxin causes an abnormally prolonged sodium channel opening in nerve membranes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Australia
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Ciguatera Poisoning*
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Electrophysiology / methods
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Humans
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Neural Conduction / drug effects
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Neurons, Afferent / drug effects
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Neurons, Afferent / physiology
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Peroneal Nerve / drug effects
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Peroneal Nerve / physiology
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Peroneal Nerve / physiopathology*
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Reference Values
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Skin / innervation
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Sural Nerve / drug effects
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Sural Nerve / physiology
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Sural Nerve / physiopathology*