Imaging of neurosarcoidosis: common, uncommon, and rare

G Bathla; A K Singh; B Policeni; A Agarwal; B Case

doi:10.1016/j.crad.2015.09.007

Imaging of neurosarcoidosis: common, uncommon, and rare

Clin Radiol. 2016 Jan;71(1):96-106. doi: 10.1016/j.crad.2015.09.007. Epub 2015 Oct 23.

Authors

G Bathla¹, A K Singh², B Policeni³, A Agarwal⁴, B Case⁵

Affiliations

¹ Department of Radiology, University of Iowa Hospitals and Clinics, IA, USA. Electronic address: girish-bathla@uiowa.edu.
² Department of Radiology, UT Health Science Center, San Antonio, TX, USA.
³ Department of Radiology, University of Iowa Hospitals and Clinics, IA, USA.
⁴ Department of Radiology, Penn State University College of Medicine, Hershey, PA, USA.
⁵ Carver College of Medicine, University of Iowa, IA, USA.

PMID: 26506463
DOI: 10.1016/j.crad.2015.09.007

Abstract

Sarcoidosis is an idiopathic inflammatory disease that may affect any organ system and have protean manifestations. Neurosarcoidosis refers to involvement of the central nervous system and may occur in patients with known sarcoidosis, or be the initial manifestation of the disease. In the latter, it can be a source of considerable confusion, given the non-specific imaging appearance. The aim of this review is to describe the imaging spectrum of neurosarcoidosis, including follow-up imaging and superimposed infections, which may occur secondary to immunosuppression. An increased awareness of this great mimicker could potentially expedite diagnosis and reduce morbidity.

Publication types

Review

MeSH terms

Central Nervous System Diseases / diagnosis*
Central Nervous System Diseases / pathology
Diagnosis, Differential
Diagnostic Imaging*
Humans
Sarcoidosis / diagnosis*
Sarcoidosis / pathology

Supplementary concepts

Neurosarcoidosis