The differential diagnosis of granulomatous epitheloid cell reaction, which is the typical histologic finding in sarcoidosis, is discussed and the involvement of the different ocular tissues illustrated. The biomicroscopic picture is compared with histopathologic findings. As the incidence of conjunctival manifestation of sarcoidosis is high (over 50% in serial sections at different levels), it represents a possibility of confirming the diagnosis histologically without any bioptic risk.