This paper presents the results of a functional-integral approach to the dynamics of a two-
state system coupled to a dissipative environment. It is primarily an extended account of …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

Background End-stage kidney disease is a leading cause of morbidity and mortality
worldwide. Prevalence of the disease and worldwide use of renal replacement therapy …

Several approaches to collaborative filtering have been studied but seldom have studies
been reported for large (several millionusers and items) and dynamic (the underlying item …

ContextDevelopers of health care software have attributed improvements in patient care to
these applications. As with any health care intervention, such claims require confirmation in …

Background The adipocyte hormone leptin is important in regulating energy homeostasis.
Since severe lipodystrophy is associated with leptin deficiency, insulin resistance …

Although it was thought that apoptotic cells, when rapidly phagocytosed, underwent a silent
death that did not trigger an immune response, in recent years a new concept of …

Historically, nutrition principles and recommendations for diabetes and related
complications have been based on scientific evidence and diabetes knowledge when …

Current guidelines identify people with chronic kidney disease (CKD) as being at high risk
for cardiovascular and all-cause mortality. Because as many as 19 million Americans may …

Trehalose is a nonreducing disaccharide of glucose that functions as a compatible solute in
the stabilization of biological structures under abiotic stress in bacteria, fungi, and …