Chondroitin sulfate proteoglycans (CSPGs) consist of a core protein and glycosaminoglycan
(GAG) chains. There is enormous structural diversity among CSPGs due to variation in the …

Perineuronal nets (PNNs) are dense extracellular matrix (ECM) structures that form around
many neuronal cell bodies and dendrites late in development. They contain several …

People with epilepsy report that stress is their most common trigger for seizures and some
believe it caused their epilepsy in the first place. The extensive preclinical, epidemiological …

Functional recovery after peripheral nerve repair in humans is often disappointing. A major
reason for this is the inaccuracy of re-innervation of muscles and sensory structures. We …

Patients with isolated unilateral pupil-sparing third or isolated fourth or sixth nerve palsies
over 50 years are often diagnosed with “microvascular extraocular palsies”. This condition …

The majority of human peripheral nerve injuries occur in the upper limb but the majority of
studies in the rat are performed in the hindlimb. The upper and lower limbs differ in dexterity …

Background Synapses are fundamental components of brain circuits and are disrupted in
over 100 neurological and psychiatric diseases. The synapse proteome is physically …

The diagnosis of epilepsy is incorrect in up to 20% of cases so should be revisited if attacks
are not responding to treatment. We present a case of long QT syndrome that remained …

Acute neurology is the neurological care that a patient receives in an emergency or urgent
care situation. This can be adapted successfully to training in a simulation where learners …

Abbr.: abnormal values in blue; AA aplastic anaemia, aGvHD acute GvHD, ALT Alanine
Aminotransferase, AZA azathioprine, BD twice a day, CSF cerebrospinal fluid, CT computer …