Huntington disease (HD) is a neurodegenerative disease caused by CAG repeat expansion
in the huntingtin gene (HTT) and involves a complex web of pathogenic mechanisms …

Huntington's disease is the most frequent autosomal dominant neurodegenerative disorder;
however, no disease-modifying interventions are available for patients with this disease. The …

Theopompus of Chios was one of the most important ancient Greek historians of the fourth
century BC. Although his work has survived only in fragments, it is still a rich and vital source …

The seer (mantis), an expert in the art of divination, operated in ancient Greek society
through a combination of charismatic inspiration and diverse skills ranging from examining …

Objective The polyglutamine diseases, including Huntington's disease (HD) and multiple
spinocerebellar ataxias (SCAs), are among the commonest hereditary neurodegenerative …

" Book IX of Herodotus' Histories provides the conclusion and climax to his work, as the
victories at Plataea and Mycale complete the improbable Greek victory over Persia. The …

Huntingtin-lowering approaches act upstream of pathogenic mechanisms and therefore
have a high a priori likelihood of modifying disease course. ASOs are already in late-stage …

Background Huntington disease (HD) is caused by an unstable CAG/CAA repeat expansion
encoding a toxic polyglutamine tract. Here, we tested the hypotheses that HD outcomes are …

The mismatch repair gene MSH3 has been implicated as a genetic modifier of the CAG·
CTG repeat expansion disorders Huntington's disease and myotonic dystrophy type 1. A …

Xenophon's Anabasis, or The Expedition of Cyrus, is one of the most exciting historical
narratives--as well as the most important autobiographical work--to have survived from …