Pathological accumulation of abnormally phosphorylated tau protein in astrocytes is a
frequent, but poorly characterized feature of the aging brain. Its etiology is uncertain, but its …

MRI red flags proposed over a decade ago by the European Magnetic Resonance Network
in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS) …

Pome fruit genetic resources collections constitute a highly valuable resource not only for
fruit breeding but also for direct use by nurseries, growers, and home gardeners. In order to …

Background Thymine kinase 2 (TK2) is a mitochondrial matrix protein encoded in nuclear
DNA and phosphorylates the pyrimidine nucleosides: thymidine and deoxycytidine …

Recent work has suggested that fibroblast growth factor-21 (FGF-21) is a useful biomarker of
mitochondrial disease (MD). We routinely measured FGF-21 levels on patients who were …

To break the juvenile stage of apple (Malus× domestica Borkh.) we transferred the LFY gene
of Arabidopsis into the genome of the apple cv.'Pinova'. A total of five transgenic clones …

Fresh berries are a popular and important component of the human diet. The demand for
high‐quality berries and sustainable production methods is increasing globally, challenging …

A set of 680 apple cultivars from the Fruit Gene bank in Dresden Pillnitz was evaluated for
the incidence of powdery mildew and scab in two consecutive years. The incidence of both …

Pain is a under‐recognized association of leucine‐rich glioma‐inactivated 1 (LGI1) and
contactin‐associated protein‐like 2 (CASPR2) antibodies. Of 147 patients with these …

PET neuroimaging of amyloid-β (Aβ) provides an in vivo biomarker for pathologic changes
associated with Alzheimer disease (AD). Aβ-targeted agents have been approved by the …