Defined in the broadest sense, Glycobiology is the study of the structure, biosynthesis,
biology, and evolution of saccharides (sugar chains or glycans) that are widely distributed in …

N-Glycans are covalently attached to protein at asparagine (Asn) residues by an N-
glycosidic bond. Although diverse sugars are attached to Asn in prokaryotes (Chapters 21 …

In the section “Synthesis of O-GalNAc Glycan Core Structures,” the following text was edited
to read:“Cosmc is an ER protein that appears to bind specifically to T synthase and ensures …

Glycans are among the most complex biological molecules found in nature, being
composed of monosaccharide units in various combinations and linkages, and featuring …

Purpose: From 1986 to 1992,''eight-drugs-in-oneday''(8-in-1) chemotherapy both before and
after radiation therapy (XRT)(54 Gy tumor/36 Gy neuraxis) was compared with vincristine …

Notch receptors function in highly conserved intercellular signalling pathways that direct cell-
fate decisions, proliferation and apoptosis in metazoans. Fringe proteins can positively and …

Scientists who plan to publish in British Journal of Pharmacology (BJP) must read this article
before undertaking a study. This editorial provides guidance for the design of experiments …

Object. Ependymomas in children continue to generate controversy regarding their
histological diagnosis and grading, optimal management, and possible prognostic factors …

Abstract WE REVIEWED THE data of children with high-stage primitive neuroectodermal
tumors (medulloblastomas) who were treated on Children's Cancer Group-921 protocol to …

PURPOSE: To evaluate prospectively the effects on survival, relapse-free survival, and
patterns of relapse of reduced-dose (23.4 Gy in 13 fractions) compared with standard-dose …