Postural instability and gait disability (PIGD) are disabling signs of Parkinson's disease.
Stereotactic surgery aimed at the internal globus pallidus (GPi) or subthalamic nucleus …

Depression is a frequent non-motor symptom of Parkinson's disease. Its prevalence varies
widely across studies (between 2.7% and 90%); around 35% have clinically significant …

Background Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans
of elderly people and is related to vascular risk factors and cognitive and motor impairment …

OBJECTIVE: To estimate clinically relevant changes in functional mobility tests and
quantitative gait measures at group and individual level in frail elderly patients. STUDY …

The role of the motor thalamus as surgical target in stereotactic neurosurgery for different
kinds of tremor is discussed. For tremor in Parkinson's disease, the subthalamic nucleus …

Parkinson's disease (PD) and multiple system atrophy (MSA) are both part of the spectrum of
neurodegenerative movement disorders and α-synucleinopathies with overlap of symptoms …

BACKGROUND: In early disease stages it can be clinically difficult to differentiate idiopathic
Parkinson's disease (IPD) from patients with multiple system atrophy predominated by …

Objective To investigate the diagnostic value of serum neurofilament light chain (NFL) in
patients with clear signs of parkinsonism but whose specific diagnosis was yet uncertain …

Objective: To investigate the relation between baseline cerebral small vessel disease (SVD)
and the risk of incident parkinsonism using different MRI and diffusion tensor imaging (DTI) …

A reliable biomarker is needed for accurate and early differentiation between Parkinson
disease and the various forms of atypical parkinsonism. We used a novel real‐time quaking …