Porphyrins, porphyrin metabolism and porphyrias. I. Update

S Thunell - Scandinavian journal of clinical and laboratory …, 2000 - Taylor & Francis
The biosynthesis of porphyrins is one of the most conserved parthways known, about the
same sequence of reactions taking place in all species. By associating different metals …

Guide to drug porphyrogenicity prediction and drug prescription in the acute porphyrias

S Thunell, E Pomp, A Brun - British journal of clinical …, 2007 - Wiley Online Library
What is already known about this subject• Many drug safety lists for acute porphyrias, largely
based on anecdotal evidence, are put forward, but no methods or rationale for the risk …

Porphyrins, porphyrin metabolism and porphyrias. IV. Pathophysiology of erythyropoietic protoporphyria-diagnosis, care and monitoring of the patient

S Thunell, P Harper, A Brun - Scandinavian journal of clinical and …, 2000 - Taylor & Francis
An extremely painful cutaneous condition with no or only slight visible skin changes,
presenting in a child or an adult as an acute reaction to sun light, is probably a manifestation …

Relationship between haemoglobin A1c in early type 1 (insulin-dependent) diabetic pregnancy and the occurrence of spontaneous abortion and fetal malformation in …

U Hanson, B Persson, S Thunell - Diabetologia, 1990 - Springer
This prospective nationwide study examined the relationship between diabetic control in
early pregnancy as assessed by HbA 1C and the incidence of spontaneous abortion and …

[HTML][HTML] Towards better process management in wastewater treatment plants: Process analytics based on SHAP values for tree-based machine learning methods

D Wang, S Thunéll, U Lindberg, L Jiang, J Trygg… - Journal of …, 2022 - Elsevier
Understanding the mechanisms of pollutant removal in Wastewater Treatment Plants
(WWTPs) is crucial for controlling effluent quality efficiently. However, the numerous …

[HTML][HTML] A machine learning framework to improve effluent quality control in wastewater treatment plants

D Wang, S Thunéll, U Lindberg, L Jiang, J Trygg… - Science of the total …, 2021 - Elsevier
Due to the intrinsic complexity of wastewater treatment plant (WWTP) processes, it is always
challenging to respond promptly and appropriately to the dynamic process conditions in …

Drugs in porphyria: From observation to a modern algorithm-based system for the prediction of porphyrogenicity

RJ Hift, S Thunell, A Brun - Pharmacology & therapeutics, 2011 - Elsevier
The acute porphyrias are a group of disorders which result from inherited defects in the
enzymes of the heme biosynthetic pathway. Affected patients are prone to potentially fatal …

[PDF][PDF] (Far) Outside the box: genomic approach to acute porphyria.

S Thunell - Physiological research, 2006 - pdfs.semanticscholar.org
If I were living in Caucasus I would be writing fairy tales there Chekov, 1888 The question of
the reasons for the extreme variation in morbidity among the gene carriers of acute …

Aminolaevulinate dehydratase porphyria in infancy. A clinical and biochemical study

S Thunell, L Holmberg, J Lundgren - 1987 - degruyter.com
Homozygous deficiency of aminolaevulinate dehydratase (porphobilinogen synthase, EC
4.2. 1.24) was diagnosed in a small child. The clinical presentation was unique since severe …

Diagnosis of acute intermittent porphyria in northern Sweden: an evaluation of mutation analysis and biochemical methods

C Andersson, S Thunell, Y Floderus… - Journal of internal …, 1995 - Wiley Online Library
Objective. To validate the use of a recently observed guanine to adenine mutation in exon
10 in the porphobilinogen deaminase (PBGD) gene as a diagnostic marker of acute …