VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy
JL Lines, LF Sempere, T Broughton, L Wang… - Cancer immunology …, 2014 - AACR
In the past few years, the field of cancer immunotherapy has made great progress and is
finally starting to change the way cancer is treated. We are now learning that multiple …
finally starting to change the way cancer is treated. We are now learning that multiple …
[HTML][HTML] Defining the signature of VISTA on myeloid cell chemokine responsiveness
TWK Broughton, MA ElTanbouly, E Schaafsma… - Frontiers in …, 2019 - frontiersin.org
The role of negative checkpoint regulators (NCRs) in human health and disease cannot be
overstated. V-domain Ig-containing Suppressor of T-cell Activation (VISTA) is an Ig …
overstated. V-domain Ig-containing Suppressor of T-cell Activation (VISTA) is an Ig …
[HTML][HTML] VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes
S Ceeraz, SK Eszterhas, PA Sergent… - Arthritis research & …, 2017 - Springer
Background In addition to activated T cells, the immune checkpoint inhibitor “V domain-
containing Ig suppressor of T-cell activation”(VISTA) is expressed by myeloid cell types …
containing Ig suppressor of T-cell activation”(VISTA) is expressed by myeloid cell types …
Defining juvenile idiopathic arthritis remission and optimum time for disease-modifying anti-rheumatic drug withdrawal: why we need a consensus
T Broughton, K Armon - Pediatric Drugs, 2012 - Springer
Juvenile idiopathic arthritis (JIA) is an autoimmune disease of childhood requiring treatment
with immune modulation therapy. It runs a relapsing and remitting course, with …
with immune modulation therapy. It runs a relapsing and remitting course, with …
Mistreatment of foreign legates and the Fetial priests: three Roman cases
TRS Broughton - Phoenix, 1987 - JSTOR
considered envoys (legati, 7rpErIEvral, K pVKES), both their own when sent to foreign
communities and those of foreign communities to themselves, to be sacred and inviolate …
communities and those of foreign communities to themselves, to be sacred and inviolate …
[BOOK][B] Letters written in a Mahratta camp during the year 1809: descriptive of the character, manners, domestic habits, and religious ceremonies, of the Mahrattas
TD Broughton - 1892 - books.google.com
Page 1 B 1,184,776 Page 2 ARTES 18371 SCIENTIA LIBRARY VERITAS OF THE
UNIVERSITY OF MICHIGAN PLURIBUS UNUN TUEBOR SI-QUERIS-PENINSULAM-AMENAM …
UNIVERSITY OF MICHIGAN PLURIBUS UNUN TUEBOR SI-QUERIS-PENINSULAM-AMENAM …
Relative age in the school year and risk of mental health problems in childhood, adolescence and young adulthood
T Broughton, K Langley, K Tilling… - Journal of Child …, 2023 - Wiley Online Library
Purpose Relative age within the school year ('relative age') is associated with increased
rates of symptoms and diagnoses of mental health disorders, including ADHD. We aimed to …
rates of symptoms and diagnoses of mental health disorders, including ADHD. We aimed to …
Roman Landholding in Asia Minor
TRS Broughton - Transactions and Proceedings of the American …, 1934 - JSTOR
According to the usual explanation the imperial estates of Asia Minor were derived in large
part directly from crown or temple lands. In this article a study of the evidence by regions and …
part directly from crown or temple lands. In this article a study of the evidence by regions and …
Safer, silencing-resistant lentiviral vectors: optimization of the ubiquitous chromatin-opening element through elimination of aberrant splicing
S Knight, F Zhang, U Mueller-Kuller… - Journal of …, 2012 - Am Soc Microbiol
Gammaretroviral and lentiviral vectors have been used successfully in several clinical gene
therapy trials, although powerful enhancer elements have caused insertional mutagenesis …
therapy trials, although powerful enhancer elements have caused insertional mutagenesis …
[HTML][HTML] Statin use is associated with a reduced incidence of colorectal cancer: a colonoscopy-controlled case–control study
T Broughton, J Sington, ILP Beales - BMC gastroenterology, 2012 - Springer
Background The aetiology of colorectal cancer (CRC) remains elusive in the majority of
cases. There is experimental evidence to show that HMG-CoA reductase inhibitors (statins) …
cases. There is experimental evidence to show that HMG-CoA reductase inhibitors (statins) …