Parkinson's disease is overdiagnosed clinically at baseline in diagnostically uncertain cases: A 3‐year European multicenter study with repeat [123I]FP‐CIT SPECT
VL Marshall, CB Reininger, M Marquardt… - Movement …, 2009 - Wiley Online Library
Overdiagnosis of Parkinson's disease (PD) is suggested by specialist review of community
diagnosis, and in postmortem studies. In specialist centers 4 to 15% of patients entered into …
diagnosis, and in postmortem studies. In specialist centers 4 to 15% of patients entered into …
Two-year follow-up in 150 consecutive cases with normal dopamine transporter imaging
VL Marshall, J Patterson, DM Hadley… - Nuclear medicine …, 2006 - journals.lww.com
Methods and results One hundred and fifty cases with normal 123 I-FP-CIT SPECT
undertaken during routine care over a 3-year period were reviewed 2.4 years (interquartile …
undertaken during routine care over a 3-year period were reviewed 2.4 years (interquartile …
[HTML][HTML] Elevated urine BMP phospholipids in LRRK2 and VPS35 mutation carriers with and without Parkinson's disease
S Gomes, A Garrido, F Tonelli, D Obiang… - npj Parkinson's …, 2023 - nature.com
Elevated urine bis (monoacylglycerol) phosphate (BMP) levels have been found in gain-of-
kinase function LRRK2 G2019S mutation carriers. Here, we have expanded urine BMP …
kinase function LRRK2 G2019S mutation carriers. Here, we have expanded urine BMP …
Emergency presentations of movement disorders
SE Gandhi, EJ Newman, VL Marshall - Practical Neurology, 2020 - pn.bmj.com
Movement disorders are typically perceived as being gradually progressive conditions that
are managed in outpatient settings. However, they may manifest de novo with an acute …
are managed in outpatient settings. However, they may manifest de novo with an acute …
Successful antiparkinsonian medication withdrawal in patients with Parkinsonism and normal FP‐CIT SPECT
VL Marshall, J Patterson, DM Hadley… - … : official journal of the …, 2006 - Wiley Online Library
Abstract Between 4% and 14% of patients diagnosed with Parkinson's disease and entering
clinical trials have normal presynaptic dopaminergic imaging. The effects of …
clinical trials have normal presynaptic dopaminergic imaging. The effects of …
Elevated urine BMPs-bis (Monoacylglycerol) Phosphates–in LRRK2 G2019S, R1441G/C and VPS35 D620N mutation carriers with and without Parkinson's disease
S Gomes, A Garrido, F Tonelli, D Obiang, E Tolosa… - medRxiv, 2022 - medrxiv.org
Background Parkinson's disease is the second most common neurodegenerative condition
and has no cure. With the emergence of targeted treatments such as LRRK2 small molecule …
and has no cure. With the emergence of targeted treatments such as LRRK2 small molecule …