Comprehensive evaluation of deep and graph learning on drug–drug interactions prediction
Recent advances and achievements of artificial intelligence (AI) as well as deep and graph
learning models have established their usefulness in biomedical applications, especially in …
learning models have established their usefulness in biomedical applications, especially in …
[HTML][HTML] Novel epigenetic techniques provided by the CRISPR/Cas9 system
N Xie, Y Zhou, Q Sun, B Tang - Stem cells international, 2018 - hindawi.com
Epigenetics classically refers to the inheritable changes of hereditary information without
perturbing DNA sequences. Understanding mechanisms of how epigenetic factors …
perturbing DNA sequences. Understanding mechanisms of how epigenetic factors …
[HTML][HTML] Genetics of progressive supranuclear palsy: a review
Y Wen, Y Zhou, B Jiao, L Shen - Journal of Parkinson's …, 2021 - content.iospress.com
Progressive supranuclear palsy (PSP) is an atypical parkinsonism with prominent 4R-tau
neuropathology, and the classical clinical phenotype is characterized by vertical …
neuropathology, and the classical clinical phenotype is characterized by vertical …
[HTML][HTML] Neural biomarker diagnosis and prediction to mild cognitive impairment and Alzheimer's disease using EEG technology
Background Electroencephalogram (EEG) has emerged as a non-invasive tool to detect the
aberrant neuronal activity related to different stages of Alzheimer's disease (AD). However …
aberrant neuronal activity related to different stages of Alzheimer's disease (AD). However …
[HTML][HTML] Identification of CHIP as a Novel Causative Gene for Autosomal Recessive Cerebellar Ataxia
Y Shi, J Wang, JD Li, H Ren, W Guan, M He, W Yan… - PloS one, 2013 - journals.plos.org
Autosomal recessive cerebellar ataxias are a group of neurodegenerative disorders that are
characterized by complex clinical and genetic heterogeneity. Although more than 20 …
characterized by complex clinical and genetic heterogeneity. Although more than 20 …
Clinical features of NOTCH2NLC-related neuronal intranuclear inclusion disease
Y Tian, L Zhou, J Gao, B Jiao, S Zhang… - Journal of Neurology …, 2022 - jnnp.bmj.com
Background Abnormal expanded GGC repeats within the NOTCH2HLC gene has been
confirmed as the genetic mechanism for most Asian patients with neuronal intranuclear …
confirmed as the genetic mechanism for most Asian patients with neuronal intranuclear …
[HTML][HTML] Polygenic analysis of late-onset Alzheimer's disease from mainland China
B Jiao, X Liu, L Zhou, MH Wang, Y Zhou, T Xiao… - PloS one, 2015 - journals.plos.org
Recently, a number of single nucleotide polymorphisms (SNPs) were identified to be
associated with late-onset Alzheimer disease (LOAD) through genome-wide association …
associated with late-onset Alzheimer disease (LOAD) through genome-wide association …
Identification of expanded repeats in NOTCH2NLC in neurodegenerative dementias
B Jiao, L Zhou, Y Zhou, L Weng, X Liao, Y Tian… - Neurobiology of …, 2020 - Elsevier
Recently, the (GGC) n repeat expansion in the NOTCH2NLC gene has been identified to be
associated with neuronal intranuclear inclusion disease (NIID). Given the clinical overlap of …
associated with neuronal intranuclear inclusion disease (NIID). Given the clinical overlap of …
Investigation of TREM2, PLD3, and UNC5C variants in patients with Alzheimer's disease from mainland China
B Jiao, X Liu, B Tang, L Hou, L Zhou, F Zhang… - Neurobiology of …, 2014 - Elsevier
Recently, 3 rare coding variants significantly associated with Alzheimer's disease (AD) risk
have been identified in western populations using whole exome sequencing method …
have been identified in western populations using whole exome sequencing method …
[HTML][HTML] A DEA-based approach for fair reduction and reallocation of emission permits
H Wu, S Du, L Liang, Y Zhou - Mathematical and computer modelling, 2013 - Elsevier
How to allocate initial emission permits is vital for the cap-and-trade system in controlling the
total emission level and improving the operation efficiency of the trade mechanism. And data …
total emission level and improving the operation efficiency of the trade mechanism. And data …