Footnotes

• Contributors VY and GS were responsible for drafting the manuscript and subsequent revisions. SP and DD provided critical revision for intellectual content. DI is guarantor of the paper.

• Competing interests None declared.

• Patient consent Detail has been removed from this case description/these case descriptions to ensure anonymity. The editors and reviewers have seen the detailed information available and are satisfied that the information backs up the case the authors are making.

• Provenance and peer review Not commissioned; externally peer reviewed. Reviewed by William Whiteley, Edinburgh, UK and Joshua Klein, Boston, USA.