We want you to find Practical Neurology helpful; helpful in assessing and investigating patients, making diagnoses, managing patients and in understanding neurological disorders. We have articles in this edition to tackle each of these.

Starting with clinical assessment, Satish Khadilkar and colleagues provide a practical approach to patients with enlarged peripheral nerves (now often found on imaging as well as on clinical examination—see page 105). Sizheng Zhao et al highlight how an unusual symptom—itching in someone with myelopathy—suggests neuromyelitis optica as the likely cause (see page 149).

Investigations usually start with blood tests. Dimitri Renard provides a useful graphic to help us interpret serum creatine kinase levels in patients with muscle disease (see page 121). Balraj Dhesi and colleagues illustrate the progressive imaging findings of neurocysticercosis (see page 135) and Simon Bell et al remind us about the clinical and radiological features of cerebral amyloid angiopathy (see page 124). Kate Wiles and …